About Accufine 5 Mg
Accufine 5 Mg contains Isotretinoin 5mg, an oral retinoid reserved for severe, nodular, or treatment-resistant acne vulgaris. It is the most effective acne treatment available, capable of achieving long-term or permanent remission in many patients.
Benefits of Accufine 5 Mg
- Highly Effective: Produces remission or cure in severe acne in up to 80% of patients after one course.
- Targets All Acne Pathways: Reduces sebum production, normalises follicular keratinisation, reduces C. acnes, and has anti-inflammatory properties.
- Long-Lasting: Many patients experience sustained remission for years after completing the course.
How Accufine 5 Mg Works
Isotretinoin is a vitamin A derivative (13-cis-retinoic acid) that binds nuclear retinoic acid receptors in sebaceous glands, dramatically reducing sebaceous gland size and sebum production. It also normalises follicular keratinisation to prevent comedone formation, reduces C. acnes colonisation, and exerts direct anti-inflammatory effects in the skin.
Dosage & Usage
- Dosage: Prescribed by a dermatologist; dose calculated per kg body weight. Take with fatty food for absorption.
- Precautions: Strictly contraindicated in pregnancy — teratogenic. Women must use two forms of contraception. Regular blood tests required during therapy.
Side Effects
- Dry lips, skin, and mucous membranes (universal)
- Elevated triglycerides or liver enzymes (monitor with blood tests)
- Photosensitivity, muscle aches, or mood changes
Consult your dermatologist before use. Not for use during pregnancy.




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