About Baclofen (Lioresal)
Baclofen (Lioresal) contains Baclofen, a muscle relaxant prescribed for spastic conditions including multiple sclerosis, spinal cord injury, and cerebral palsy. It reduces painful muscle spasm and stiffness, improving mobility and quality of life when used under medical supervision.
Benefits of Baclofen (Lioresal)
- Spasm Relief: Effectively reduces muscle hypertonicity and spasm.
- Improved Mobility: Enables better movement and physical function.
- Pain Reduction: Decreases spasm-associated musculoskeletal pain.
How Baclofen (Lioresal) Works
Baclofen is a GABA-B receptor agonist that inhibits presynaptic calcium influx and reduces the release of excitatory neurotransmitters at spinal cord interneurons. This selectively reduces spastic hypertonicity without significantly impairing voluntary motor function.
Dosage & Usage
- Dosage: As prescribed by your doctor; start at the lowest effective dose.
- Precautions: Avoid abrupt discontinuation; may cause drowsiness — avoid driving.
Side Effects
- Drowsiness or dizziness
- Weakness or dry mouth
- Hypotension (especially tizanidine)
Consult your doctor before use.



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